The Integrated RCH Apheresis service – A Centre of Excellence

Dr Anthea Greenway, the Head of Clinical Haematology and Clinical Lead for the RCH Apheresis Service, describes apheresis as the process of ‘cleaning or separating the blood.’ 

“Basically, we are using a special machine called the Terumo Spectra Optia Apheresis System to separate the blood into its separate components. This machine spins the blood at a rapid speed which helps us to separate it into layers. Each one of those layers of the blood can contribute to how we might look after a patient with a range of different conditions, from cancers or leukaemia and blood disorders to kidney and neurological diseases” Anthea shared. 

The Terumo Spectra Optia Apheresis System makes this procedure as efficient and effective as possible. This state-of-the-art device, generously funded by 3AW and the Good Friday Appeal, has allowed clinical staff to further prioritise patient care and treat even more patients.  

Terumo Spectra Optia Apheresis System

“One of the incredible things about Apheresis is that we can treat a broad range of conditions, so that’s why the use of Apheresis has continues to grow quickly,” Anthea further explained.   

Access to this treatment is vital as it can be used to assist countless patients across the RCH, including those undergoing stem cell transplants, leukaemia treatment and those being treated for sickle cell disease. It can also assist with the management of organ rejection and dysfunction following transplantation and with life threatening kidney and neurological diseases. 

“We have set up an interdisciplinary service where we have an amazing group of nursing staff, scientists and clinicians who move across all those different work areas. Together, we share our expertise and medical knowledge so we can provide the best care to our patients,”

Dr Anthea Greenway

“Previously, and in other centres where this is set up as a separated system, it has been challenging to maintain coverage across all disease groups and specialties. It’s also hard to provide in-depth experience and service to make sure we’re giving great care to our patients,” she continued.   

This interdisciplinary model is an Australian-first, helping maximise staff expertise and focus on the needs of each child. Additionally, the service is widely recognised for its ability to deliver patient-centred care in the RCH’s Ambulatory Day Medical Centre.  

“The Ambulatory Day Centre allows patients to come from the ward or from home to have their treatment. This space offers them a family-friendly environment as it accommodates the parents, offers education, art therapy and more,” Anthea shared. 

The outpatient setting of the Ambulatory Day Centre also reduces the need for intensive hospital stays, providing patients with more flexible care.  

“The day medical centre allows us to, where appropriate, de-escalate and free up resources for other children that need them. Many of our patients are still coming in and doing schoolwork, therapy and normal kid activities,” Anthea highlighted.

Dr Anthea Greenway

The Apheresis Service is helping save and transform the lives of sick children in a way that was not possible a decade ago.  

“Some of my patients were only able to walk with a crutch or couldn’t participate in sport. But once they started this treatment, they have been able to throw away that crutch, perform at a high-level in sports and thrive at school, including completing their exams,” Anthea emphasised. 

The Apheresis Service has also been able to address the need for an after-hours service by offering training and education programs that were not previously available in the country. This is helping cultivate a sustainable workforce of dedicated Australian healthcare professionals that can support even more sick children across the country. 

“Establishing the Apheresis Service with an emphasis on education, training and quality has been really important in maintaining excellent care for our patients,” Anthea said. 

“In a hospital such as the RCH which provides care to all children across Melbourne, regional Victoria and beyond, access to an excellent paediatric apheresis service is critical in ensuring we’re providing the best possible care,” Anthea added. 

The RCH’s Apheresis Service is now at the forefront of paediatric excellence. Thanks to the support of the Good Friday Appeal and 3AW, the RCH has been able to provide world-class treatment to sick children and is now better equipped to respond to new developments in healthcare.  

“We absolutely appreciate the Good Friday Appeal’s support in this critical endeavour, and it would not have been possible without their help.” 

Last updated March 2025

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RCH TV Program for Patients and Families

Made possible thanks to support from Woolworths and the Good Friday Appeal, The Royal Children’s Hospital (RCH) is keeping patients engaged, connected, and educated through RCH TV. 

Through the in-house TV shows Be Positive and Hospital Lingo, RCH TV helps to promote children’s understanding of hospital and healthcare experiences, while also empowering children and creating a positive hospital experience. 

In the past year, hundreds of patients have tuned in each week to watch Hospital Lingo from their hospital beds, with 731 winners since July 1 2024.  A child’s guide to hospital videos have received 86.6 million views on YouTube and they are watched in 176 countries (there are only 195 countries in the world). 

Be Positive (B+) is the Hospital’s in-house TV program helping kids find out more about the RCH. Host Carlie and her two curious puppet friends, Jazz and Rocco, help children and young people learn and understand more about hospital, including what might happen during their stay. It includes video series like A child’s guide to hospital, Get to know the people, and Get to know the RCH.  

In our video, A child’s guide to hospital: CAR T Cell Apheresis, the RCH TV team had the honour of featuring a remarkable young patient. This courageous individual took centre stage to provide firsthand insights into CAR T Cell Apheresis, offering a unique perspective from a child’s point of view. The involvement of this talented patient not only enriches the video content but also serves as a source of inspiration and comfort for other children facing similar medical journeys. 

Following the filming, the patient’s mother provided this quote: 

“Thank you again for offering my daughter such a wonderful opportunity today. There were times during her first relapse when she was in the depths of hell and had absolutely zero joy in her life. And yet, here she was today, recreating some of her treatment with such a big smile on her face. On the way home she was reflecting about all the great opportunities she’s had because of her cancer. I strongly believe that the positive opportunities she’s had at the RCH (like pursuing her passion for acting/film) have been a tonic for some of that trauma. So, I hope you know how much we appreciate your support and encouragement.” 

Hospital Lingo is a live game show that airs three times a week directly to patient rooms. This educational game, which is like bingo but with the weird and wonderful things found in hospital, keeps patients engaged, connected and distracted while allowing them to win prizes. 

Since July 1 2024, there have been 731 winners of Hospital Lingo.

“Hospital Lingo is a game show that brings so much joy to children who find themselves in hospital. It is wonderful to witness how Hospital Lingo has helped many children who are initially scared about being in hospital to become empowered, confident and knowledgeable about their healthcare experience.  How lucky am I to be a part of a TV show that can change the experience of children in hospital for the better.” 

Carlie Alicastro, Child Life Therapist and Host, RCH TV.

As well as patients accessing the RCH TV resources in hospital, both via their TV and through the Child Life Therapy team, the resources are available and widely accessed by patients and families across Australia through the RCH website and YouTube.   

A child’s guide to hospital videos have received 86.6 million views on YouTube.  They are watched in 176 countries (there are only 195 countries in the world).

Impact Milestones

2026 Project update:

Over the past year, RCH TV was able to achieve the following successes:

  • RCH TV was able to successfully deliver over five new videos which have helped educate both children and families about important healthcare topics, from prosthetics to apheresis cell collections.
  • To help maximise the reach of this content, RCH TV strategically promoted its videos across the hospital, ensuring that families were empowered to learn about specific procedures when needed most. For instance, relevant QR codes were placed on posters in specialist clinics.
  • TV segments attracted close to 4.7 million video views, resulting in close to 100 million total video views reached.
  • Hospital Lingo, the program’s live game show, also continued to air three times a week directly to patient rooms. This educational game, continued to keep patients and their families engaged, connected, and distracted.
  • The program uses a Bingo format to demystify hospital equipment, with medical patients and their siblings able to engage in the live show from their rooms and phone in when they are winners.
  • During this period, there were 1,521 winners of Hospital Lingo, and on 19 occasions a patient joined the show as a co-host.
  • RCH TV has been in production for 34 years, having evolved and expanded over time. The project remains the RCH’s most visible and utilised child-centred content with significant global reach, helping alleviate anxiety and promote understanding for sick children all over.
2023/2024
  • Five educations A child’s guide to hospital… videos were created and published on topics including EEG, VEM, the Burns Clinic, and the MOCK MRI.  
  • One video was produced specifically for nurses around confidentiality  
  • A QR Code to access medical imaging specific A child’s guide to hospital videos were added to all medical imaging appointment letters. Data collection showed that with the QR Code, engagement increased by 38.2 per cent. Due to this success, a QR Code will now be added to all specialist clinic appointment letters.  
  • Since July 1 2024, there have been 731 winners of Hospital Lingo  
2022/2023
  • Seven educational videos were created and published for Be Positive (B+). They were published on the inpatient TV channel, the RCH TV website and the RCH YouTube channel.   
  • Across this period, RCH TV segments attracted approximately 8.4 million views on the RCH YouTube channel.   
  • Hospital Lingo continued to be broadcast every Tuesday, Wednesday and Thursday. On several occasions, inpatients were invited to come into the studio and guest host the show. Multiple parents wrote to the RCH TV team to share how impactful Hospital Lingo is for their children.  
  • The content produced through RCH TV remains the most visible and utilised child centred content available from the RCH.   
2021/2022
  • Five educational videos were created and published for Be Positive (B+). They were published on the inpatient TV channel, the RCH TV website and the RCH YouTube channel.   
  • Across this period, RCH TV segments attracted approximately 14.5 million views on the RCH YouTube channel.   
  • Hospital Lingo continued to be broadcast every Tuesday, Wednesday and Thursday. On several occasions, inpatients were invited to come into the studio and guest host the show, where possible with ongoing COVID-19 restrictions. 

Last updated February 2026.

Program proudly supported by the Woolworths team and customers

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A National Centre of Excellence in Speech Genetics: Transforming Patient Care

Even with intense therapy, children with apraxia have severely impaired speech development, which has lifelong impacts on literacy, educational and employment outcomes. 

Thanks to funding provided by the Good Friday Appeal, clinician researchers from The Royal Children’s Hospital and the Murdoch Children’s Research Institute are establishing a speech genetics clinic for speech apraxia.

The new clinic will draw on expertise in speech pathology, neurology, neuropsychology and clinical genetics.

The centre will transform standard practice for children with debilitating speech apraxia, moving from the current ‘watch and wait’ surveillance, or ‘trial and error’ symptom-based therapies, toward precision medicine, with a focus on genetic testing, advancing detection, diagnosis, genetic counselling, earlier targeted intervention and even prevention. 

This will improve life outcomes for children at the Royal Children’s Hospital and across the country.

Posted June 2020

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Transforming Clinical Care to Improve Mental Health for Patients: Phase Two

Hospital stays can be scary times for both children and their parents, regardless of age and experience. New people, strange equipment and an unfamiliar environment are a lot to take in.

Supported by the Good Friday Appeal, this hospital-wide project will utilise evidence about emotional development and behavioural responses to stress, to up-skill clinicians to consider the mental health impact of every procedure and interaction they have with a child.

The project, which focuses on the zero to five-year age group was successfully piloted on the Koala (Cardiac Surgery) and Cockatoo (Surgical and Neuro Care) wards. It uses evidence-based strategies to equip clinicians to deliver great care by training them to:

  • communicate with young children
  • approach care in ways that reduce psychological harm
  • recognise deterioration in mental health in patients and their families
  • engage distressed parents to support their child

Thanks to your generosity, supporting the mental health of infants and young children at the Royal Children’s Hospital will become part of routine care.

Posted June 2020

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Children’s Cancer Centre Tissue Bank

The Children’s Cancer Centre (CCC) Tissue Bank collects solid tumour, blood and bone marrow samples from oncology patients to learn more about cancer in children.

The tissue bank staff work in collaboration with hospitals, laboratories and researchers both locally and internationally to translate those findings into potentially life-saving treatments.

“Samples are preserved with the utmost care and dignity for future clinical and research purposes. Over 50 staff including consultants, surgeons, haematologists, oncologists, specialist pathologists, researchers and research enablers work together as part of the team,” said Louise Ludlow, CCC Tissue Bank Coordinator.

“Together we are committed to improving the survival rate and long term health outcomes for children diagnosed with cancer.”

In addition to the processing of samples for clinical trials, the CCC Tissue Bank also prepares clinical samples for further molecular testing (testing for certain genes, proteins, or other molecules in a tissue sample) as standard of care.

Thanks to donor support, the CCC Tissue Bank has also participated in important research projects outside of the Melbourne Children’s campus, including research conducted by St. Jude Children’s Research Hospital in the Memphis USA, The Hospital for Sick Children in Toronto, Canada, and the Kid’s Cancer Centre, Sydney Children’s Hospital.

“The Tissue Bank is an invaluable resource which allows us to collaborate in adequately powered international studies through sample and knowledge sharing, ensuring that we remain at the forefront of cutting edge paediatric cancer research,” Louise said.

Posted June 2020

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Pathology Tissue Processors

Thanks to the generous support of the Good Friday Appeal and 3AW’s Neil’s Wheel participants, the Royal Children’s Hospital (RCH) Lab Services has a new tissue processing machine.

Featuring an upgraded model for preserving tissue samples and a highly specific microtomy device for slicing and setting the samples for analysis, these new technologies will greatly increase the speed an accuracy of processing tissue samples. 

For RCH patients, this means faster and more accurate diagnoses and a reduction in need for unnecessary and painful surgeries, with the new ability to do more with smaller tissue samples.

The two parts of the machine have been named ‘Neil’ and ‘Mitchell’ by the RCH Lab Services Team to thank Neil Mitchell, 3AW radio presenter, for his ongoing support of the Hospital.

The 2020 Neil’s Wheel fundraiser raised $213,000 for the Good Friday Appeal to fund this machine. 

Posted June 2020

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The Kidney Flagship

Bringing together researchers from the Hospital and the Murdoch Children’s Research Institute (MCRI), the Kidney Flagship aims to reduce the burden of genetic kidney disease on patients and their families by improving diagnosis and treatment, and the development of new targeted therapies.

The new clinical pipeline will see kidney patients with suspected genetic disease undergo a genomic test that can easily be added to routine blood tests. In many cases this test will be able to find the genetic change and identify how or why kidney disease occurred.

It will also reduce the need for unnecessary biopsies and mean less time in hospital for patients.

Following this test, researchers will be able to grow or ‘model’ the disease in a lab and aim to identify targeted treatments for the patient.

Ultimately, this could lead to the development of a drug or treatment that could improve outcomes for all kidney patients.

Posted May 2020

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Neurosurgery Microscope

For the highly trained neurosurgeons at The Royal Children’s Hospital (RCH), operating microscopes are essential tools during these procedures for providing light and magnification during surgery.

Thanks to the generous community of the Good Friday Appeal supporters on Giving Tuesday, the RCH Neurosurgery Department will upgrade its equipment with a new operating microscope that includes the latest technological features to help save children’s lives.

The new hybrid microscope has advanced functions including an endoscope attachment which surgeons can use to identify tumours that are out of the normal field of view and improve access to regions of the brain that were previously difficult to reach.

It also features 3D technology so surgeons can operate in ergonomic positions and enhance educational opportunities in theatre.

Posted May 2020

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